World is increasingly moving towards frozen embryo transfer cycles due to various reasons. Serum progesterone levels on the day of embryo transfer (ET) in fresh donor in vitro fertilisation (IVF)/ICSI cycles were positively correlated with clinical pregnancy and live birth rates. Progesterone as pregnancy support has been extensively studied and co-related with achieving a successful clinical pregnancy. Keeping this in mind, we need to provide progestational support. Also the increased use of gonadotropin analogues to prevent premature luteinising hormone (LH) surge adds to the deficit. In the era of assisted reproduction, during the process of ovum pick up, we remove the granulosa cells which leads to a progesterone deficiency. Initially, in the first phase, corpus luteum provides support for embryo to implant and grow and later this role is taken over by the placenta. Once the embryo prepares for implantation, progesterone comes into play and supports the process. Progesterone is a sex steroid needed for maintaining pregnancy. Progesterone as a hormone is required for embryo implantation and carrying on a pregnancy. A prospective study to correlate serum progesterone levels and clinical pregnancy outcome in frozen embryo transfer cycles.
#Estrogen and progesterone levels before fet how to
How to cite this URL: Chawla R, Kunjimoideen K.
How to cite this article: Chawla R, Kunjimoideen K. Keywords: Clinical pregnancy rate, FET, serum progesterone Level in blood on the day of starting progesterone to obtain a positive clinical pregnancy was 0.21 ng/mL and should not exceed 0.96 ng/mL. Conclusion: Serum p4 should be between 1.5 and 24 ng/mL on the starting day for a positive result. Results: Clinical pregnancy rate was 32.69% in group A vs 24% in the other group which is non-significant. Statistical tests like chi square test and Mann-Whitney test were applied and SPSS version 23 was used. No measurement of serum p4 was undertaken in the other group (B). Blood levels of p4 were measured when beginning progesterone and on the day of Frozen embryo transfer (FET) in one group and were supplemented if levels were less than 10 ng/mL. Methods: Total 100 patients were included in the study and divided into two groups (A and B).
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